Comparison

Human CCR8 Protein, Flag,His Tag&Twin-Streptavidin Tag (Nanodisc) European Partner

Item no. CC8-H52D7-100ug
Manufacturer ACROBiosystems
Amount 100 ug
Quantity options 100 ug 20 ug
Category
Type Proteins Recombinant
Format Liquid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Unconjugated, Streptavidin, FLAG
Purity 90%
Dry ice Yes
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping Condition Dry ice
Available
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
N-Flag & C-10xHis & C-Twin Strep, Unconjugated
Shipping Temperature
Dry ice
Storage Conditions
-70°C
Molecular Weight
62.0 kDa
Manufacturer - Format
Liquid
Description
Human CCR8 Protein, Flag, His Tag&Twin-Streptavidin Tag (CC8-H52D6) is expressed from human 293 cells (HEK293). It is a membrane protein, contains complete wild type 7-transmembrane domans (TMD) and extracellular doman (ECD).
Background
This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.
Molecule
CCR8
Exp Region
Asp 2 – Ser 345
Characteristics
This protein carries a Flag tag at the N-terminus, and a polyhistidine tag at the C-terminus, followed by a twin streptavidin tag. The protein has a calculated MW of 62.0 kDa.
Endotoxin
1.0 EU per μg
Buffer
20 mM HEPES, 150 mM NaCl, pH7.5
Stability
● The product MUST be stored at -70°C or lower upon receipt
● -70°C for 3 months under sterile conditions.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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