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Human Claudin-4 Protein, His,Twin-Streptavidin Tag (Detergent)

Human Claudin-4 Protein, His,Twin-Streptavidin Tag (Detergent)

Item no.	CL4-H5587-20ug
Manufacturer	ACROBiosystems
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	Insect Cells
Conjugate/Tag	Unconjugated, Twin-Streptavidin
Purity	90%
Formula	50 mM Tris, 150 mM NaCl, DDM, CHS, pH7.5
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Dry ice
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-10xHis & C-Twin-Strep, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	27.5 kDa
Manufacturer - Format	Liquid
Description	The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Background	The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Molecule	Claudin-4
Exp Region	Met 1 - Val 209
Characteristics	This protein carries a polyhistidine tag at the N-terminus and a twin streptavidin tag at the C-terminus. The protein has a calculated MW of 27.5 kDa. The protein migrates as 25-27 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 150 mM NaCl, DDM, CHS, pH7.5
Stability	● The product MUST be stored at -70°C or lower upon receipt ● -70°C for 12 months under sterile conditions.
Protectant	glycerol

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CL4-H5587-20ug-datasheet.pdf

CL4-H5587-20ug-safety-datasheet.pdf