[Novoprotein] Recombinant Human Cocaine- & Amphetamine-Regulated Transcript/CARTPT (C-6His)

Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.

Recombinant Human CARTPT is produced by our Mammalian expression system & the target gene encoding Gln28-Leu116 is expressed with a 6His tag at the C-terminus.

Cocaine- & Amphetamine-Regulated Transcript Protein (CARTPT) is a secreted protein that belongs to the CART family. CARTPT is detected in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, & also found in terminals in the periventricular part of the paraventricular nucleus. CARTPT is processed by prohormone/proprotein convertases to produce smaller, biologically active peptides. CARTPT is a satiety factor closely associated with the actions of leptin & neuropeptide Y. This anorectic peptide inhibits both normal & starvation-induced feeding & completely blocks the feeding response induced by neuropeptide Y & regulated by leptin in the hypothalamus. CARTPT promotes neuronal development & survival in vitro.

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.