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CILP Recombinant Protein

CILP Recombinant Protein

Item no.	OPCD02224
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism By Cell Type Blastoma Carcinoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Mesothelioma Immunoprecipitation Western Blot ELISA Endocrine Regulation of Lipid Metabolism SDS-PAGE By Organ Colorectal Cancer
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS, GST
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	9830114D16;C130036G17Rik;cartilage intermediate layer protein 1;CILP-1.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His and GST Tag
Molecular Weight	60kDa
Gene symbol	Cilp
Gene Fullname	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).
Nucleotide accession_num	NM_173385.2
Protein accession_num	NP_775561.1
Protein name	Cartilage intermediate layer protein 1
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD02224-datasheet.pdf

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Amount: 10 ug

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Delivery expected until 10/30/2025

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