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TNFRSF1B Recombinant Protein (Human)

TNFRSF1B Recombinant Protein (Human)

Item no.	OPED00140
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Targets for Rodent Neurosciences By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis ELISA Autophagy Immunostaining
Type	Proteins Recombinant
Format	Lyophilized
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	HEK293 cells
Purity	>95% (SDS-PAGE)
Citations	Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors: N. Holler, et al.; J. Immunol. MethodsÂ 237, 159 (2000),Â Abstract;
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD120b;p75;p75 TNF receptor;p75TNFR;p80 TNF-alpha receptor;soluble TNFR1B variant 1;TBPII;TNFBR;TNFR1B;TNFR2;TNF-R2;TNF-R75;TNFR80;TNF-RII;TNF-R-II;tumor necrosis factor beta receptor;tumor necrosis factor binding protein 2;tumor necrosis factor receptor 2;tumor necrosis factor receptor superfamily member 1B;tumor necrosis factor receptor type II.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Protein
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Shipping Temperature	Wet Ice
Molecular Weight	75 kDa
Manufacturer - Application Additional Information	ELISA: binds to TNF-alpha. Detection of membrane-bound TNF-alpha in combination with PAb to human IgG1 (e.g. ALX-211-502 (Biotin)).
Gene symbol	TNFRSF1B
Gene Fullname	TNF receptor superfamily member 1B
Protein size	Recombinant
Product format	Lyophilized. Contains PBS.
Reconstitution and storage	Reconstitute with 50 ul sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. Store at -20C
Description of target	Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Nucleotide accession_num	NM_005345.5
Protein accession_num	NP_005336.3
Protein name	Tumor necrosis factor receptor superfamily member 1B

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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