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Recombinant Human Myostatin

Recombinant Human Myostatin

Manufacturer	ProSpec
Category	Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Specific against	Human
Amount	2ug
Item no.	cyt-418-2ug
eClass 6.1	32161000
eClass 9.0	42030690
Available
Synonyms	GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy
Introduction	GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
Description	Myostatin Human Recombinant produced in E.Coli is a homodimer, non-glycosylated polypeptide chain containing 2 x 109 amino acids and having a total molecular mass of 24814 Dalton. The GDF-8 is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a concentrated (1mg/ml) solution containing no additives.
Purity	Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Amino acid sequence	The sequence of the first five N-terminal amino acids was determined and was found to be Asp-Phe-Gly-Leu-Asp.
Biological Activity	The ED50 as determined by the inhibition of the proliferation of MPC-11 cells is 20ng/ml, corresponding to a Specific Activity of 50, 000units/mg.
Storage	Lyophilized Myostatin although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Myostatin should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2ug

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Delivery expected until 6/20/2024