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Human Lefty2 / Lefty A Protein (Fc Tag)

Human Lefty2 / Lefty A Protein (Fc Tag)

Manufacturer	Sino Biological
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Amount	2mg
Host	Human
Item no.	10248-H01H-2
eClass 6.1	34160400
eClass 9.0	42020190
Available
Molecule	Lefty2
Synonym	EBAF, LEFTA, LEFTYA, TGFB4
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the mature form of human LeftyA (NP_003231.2) (Phe 78-Pro 366) was fused with the Fc region of human IgG1 at the N-terminus.
Expressed Host	Human Cells
Purity	> 90 % as determined by SDS-PAGE
Bio-Activity	Measured by its ability to inhibit recombinant human BMP4 induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 4-16 ug/mL in the presence of 50 ng/mL of recombinant human BMP4.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Glu 20
Molecule Mass	The recombinant human LeftyA/Fc is a disulfide-linked homodimer The reduced monomer consists of 526 amino acids and has a predicted molecular mass of 58.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh LeftyA/Fc monomer is approximately 70 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_003231.2
Amino acid sequence	Phe78-Pro366
TAG	N-human IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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10248-H01H-2-datasheet.pdf

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Amount: 2mg

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Delivery expected until 5/30/2024