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Recombinant Human Leptin Receptor Protein (His & hFc Tag), HPLC-verified

Recombinant Human Leptin Receptor Protein (His & hFc Tag), HPLC-verified

Item no.	10322-H03H-4
Manufacturer	Sino Biological
Amount	4 mg
Quantity options	1 mg 100 ug 2 mg 4 mg
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins Obesity Endocrine Regulation of Lipid Metabolism
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD295, LEP-R, LEPRD, OB-R, OBR
Similar products	LEPR
Available
Manufacturer - Category	Protein
Molecule	LEPR
Synonym	CD295, LEP-R, LEPRD, OB-R, OBR
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Asp 839) of human leptin receptor precursor (NP_002294.2) was expressed with the C-terminal fused polyhistidine-tagged Fc region of human IgG1.
Expressed Host	Human Cells
Purity	> 90 % as determined by SDS-PAGE
Bio-Activity	Measured by its binding ability in a functional ELISA . Immobilized human Leptin at 1.25 ug/ml (100 ul/well) can bind human Leptin receptor with a linear range of 0.032-4.0 ug/ml .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Phe 22
Molecule Mass	The recombinant human LEPR/Fc is a disulfide-linked homodimeric protein.The reduced monomer consists of 1065 amino acids and has a predicted molecular mass of 121.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh LEPR/Fc monomer is approximately 155-165 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_002294.2
Amino acid sequence	Met1-Asp839
TAG	C-human IgG1-Fc & His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 4 mg

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