« Back
Home /
Research Area /
Metabolism /
Recombinant Human IL-6R Protein (ECD, His Tag), HPLC-verified

Recombinant Human IL-6R Protein (ECD, His Tag), HPLC-verified

Item no.	10398-H08H-2
Manufacturer	Sino Biological
Amount	2 mg
Quantity options	1 mg 100 ug 2 mg 4 mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis By Cell Type Carcinoma Hematology Leukemia Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis
Type	Proteins
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD126, gp80, IL-6R, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ
Similar products	IL6R
Available
Manufacturer - Category	Protein
Molecule	IL6R
Synonym	CD126, gp80, IL-6R, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain of human IL6R (NP_000556.1) corresponding to amino acid (Met 1-Pro 365) was expressed with a C-terminal polyhistidine tag.
Expressed Host	Human Cells
Purity	> 90 % as determined by SDS-PAGE
Bio-Activity	1. Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL-6 at 8 ug/mL (100ul/well) can bind recombinant human IL6R with a linear range of 1.25-20.0 ng/ml. 2. Measured by its ability to enhance the IL6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 20-80 ng/ml.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Leu 20
Molecule Mass	The soluble form of recombinant human IL6R consists of 357 amino acids and has a predicted molecular mass of 40 kDa. In SDS-PAGE under reducing conditions, it migrates with an apparent molecular mass of 60-65 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_000556.1
Amino acid sequence	Met1-Pro365
TAG	C-His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

10398-H08H-2-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 2 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question