Comparison

Recombinant Human IL-2R beta/CD122 Protein (ECD, hFc Tag), HPLC-verified European Partner

Item no. 10696-H02H-4
Manufacturer Sino Biological
Amount 4 mg
Quantity options 1 mg 100 ug 2 mg 4 mg
Category
Type Proteins
Specific against Human (Homo sapiens)
Host Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD122, IL15RB, P70-75
Similar products IL2RB
Available
Manufacturer - Category
Protein
Molecule
IL2RB
Synonym
CD122, IL15RB, P70-75
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the extracellular domain (Met 1-Asp 239) of human IL2 Rbeta (NP_000869.1) precursor was expressed with the C-terminal fused Fc region of human IgG1.
Expressed Host
Human Cells
Purity
> 90 % as determined by SDS-PAGE
Bio-Activity
1. Measured by its ability to bind biotinylated recombinant rat IL2 in a functional ELISA.
2. Using the Octet RED System, the affinity constant (Kd) of Human IL2RB-Fc (Cat:10696-H02H) bound to Human IL2 was 0.8nM.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Ala 27
Molecule Mass
The recombinant human IL2 Rbeta/Fc is a disulfide-linked homodimeric protein generated after removal of the signal peptide. The reduced monomer consists of 451 amino acids and has a predicted molecular mass of 51.6 kDa. As a result of glycosylation, the apparent molecular mass of rh IL2RB/Fc monomer is approximately 60-65 kDa in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4
Accession
NP_000869.1
Amino acid sequence
Met1-Asp239
TAG
C-human IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 4 mg
Available: In stock
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