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Recombinant Human TIMP-1 Protein (His Tag)

Recombinant Human TIMP-1 Protein (His Tag)

Item no.	10934-H08H-4
Manufacturer	Sino Biological
Amount	4 mg
Quantity options	1 mg 100 ug 2 mg 20 ug 4 mg
Category	Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CLGI, EPA, EPO, HCI, TIMP, TIMP-1
Similar products	TIMP1
Available
Manufacturer - Category	Protein
Molecule	TIMP1
Synonym	CLGI, EPA, EPO, HCI, TIMP, TIMP-1
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the human TIMP1 (NP_003245.1) (Met 1-Ala 207) with a C-terminal polyhistidine tag was expressed.
Expressed Host	Human Cells
Purity	> 97 % as determined by SDS-PAGE
Bio-Activity	Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2 (R&D Systems, Catalog # ES001) . The IC50 value is < 6 nM.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Cys 24
Molecule Mass	The secreted recombinant human TIMP1 comprises 195 amino acids with a predicted molecular mass of 22 kDa. As a result of glycosylation, rhTIMP1 migrates as an approximately 30 kDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_003245.1
Amino acid sequence	Met1-Ala207
TAG	C-His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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