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Recombinant Human IL-10RB/IL-10R beta Protein (His & hFc Tag), HPLC-verified

Recombinant Human IL-10RB/IL-10R beta Protein (His & hFc Tag), HPLC-verified

Item no.	10945-H03H-1
Manufacturer	Sino Biological
Amount	1 mg
Quantity options	1 mg 100 ug 2 mg 4 mg
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
Similar products	IL10RB
Available
Manufacturer - Category	Protein
Molecule	IL10RB
Synonym	CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	DNA sequence encoding the extracellular domain (Met 1-Ser 220) of human IL10Rbeta (NP_000619.3) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 92 % as determined by SDS-PAGE
Bio-Activity	Measured by its binding ability in a functional ELISA . Immobilized human IL28B at 20 ug/ml (100 ul/well) can bind human IL10RB-Fc with a linear ranger of 3.125-25 ug/ml.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Met 20
Molecule Mass	The recombinant human IL10Rbeta/Fc is a disulfide-linked homodimer. The reduced monomer consists of 449 amino acids and has a predicted molecular mass of 51.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhIL10Rbeta/Fc monomer is approximately 75-85 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_000619.3
Amino acid sequence	Met1-Ser220
TAG	C-human IgG1-Fc & His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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