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Mouse PD1 / PDCD1 Protein (His & Fc Tag)

Mouse PD1 / PDCD1 Protein (His & Fc Tag)

Item no.	50124-M03H-1
Manufacturer	Sino Biological
Amount	1 mg
Quantity options	1 mg 2 mg 4 mg
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Peptides & Proteins Recombinant Proteins Myelofibrosis
Type	Proteins
Specific against	Mouse (Murine, Mus musculus)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Ly101, PD-1, Pdc1
Similar products	PDCD1
Available
Molecule	PDCD1
Synonym	Ly101, PD-1, Pdc1
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Gln 167) of mouse PDCD1 (NP_032824.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 90 % as determined by SDS-PAGE, with approximately 10 % free Fc fragment.
Bio-Activity	Measured by its binding ability in a functional ELISA . Immobilized recombinant mouse PD1-L1 at 1 ug/ml (100 ul/well) can bind mouse PD1 with a linear range of 6.25-400 ng/ml .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Leu 25
Molecule Mass	The recombinant mouse PDCD1/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 391 amino acids and has a predicted molecular mass of 44.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm PDCD1/Fc monomer is approximately 60-65 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_032824.1
Amino acid sequence	Met1-Gln167
TAG	C-human IgG1-Fc & His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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