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Recombinant Mouse FGFR1 Protein (hFc Tag), HPLC-verified

Recombinant Mouse FGFR1 Protein (hFc Tag), HPLC-verified

Item no.	50186-M02H-1
Manufacturer	Sino Biological
Amount	1 mg
Quantity options	1 mg 100 ug 2 mg 4 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Regulation of Appetite By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Astrocytoma
Type	Proteins
Specific against	Mouse (Murine, Mus musculus)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AW208770, bFGF-R-1, c-fgr, Eask, Fgfr-1, FLG, Flt-2, Hspy, MFR
Similar products	FGFR1
Available
Manufacturer - Category	Protein
Molecule	FGFR1
Synonym	AW208770, bFGF-R-1, c-fgr, Eask, Fgfr-1, FLG, Flt-2, Hspy, MFR
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Glu 376) of mouse FGFR1 isoform 1 (P16092-1) was as fused with the Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 97 % as determined by SDS-PAGE
Bio-Activity	Measured by its ability to inhibit mouse FGF acidic (aFGF/FGF1) dependent proliferation of Balb/C 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.1-0.6 ng/ml.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Arg 22
Molecule Mass	The secreted recombinant mouse FGFR1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 596 amino acids and has a calculated molecular mass of 66.5 kDa. The apparent molecular mass of rmFGFR1/Fc monomer is approximately 100-110 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	P16092-1
Amino acid sequence	Met1-Glu376
TAG	C-human IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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