Comparison

Recombinant Mouse ACVR2A Protein (His & hFc Tag) European Partner

Item no. 50613-M03H-4
Manufacturer Sino Biological
Amount 4 mg
Quantity options 1 mg 2 mg 200 ug 4 mg
Category
Type Proteins
Specific against Mouse (Murine, Mus musculus)
Host Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ActrIIa, Acvr2, TactrII
Similar products ACVR2A
Available
Manufacturer - Category
Protein
Molecule
ACVR2A
Synonym
ActrIIa, Acvr2, TactrII
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the extracellular domain of mouse ACVR2A (NP_031422.3) (Met 1-Pro 134) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host
Human Cells
Purity
> 97 % as determined by SDS-PAGE
Bio-Activity
Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation.
The ED50 for this effect is typically 20-60 ng/mL in the presence of 10 ng/mL recombinant Activin A.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Ala 20
Molecule Mass
The secreted recombinant mouse ACVR2A/Fc chimera is a disulfide-linked homodimer. The reduced monomer comprises 363 amino acids and has a calculated molecular mass of 41.4 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 55-65 kDa band in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4
Accession
NP_031422.3
Amino acid sequence
Met1-Pro134
TAG
C-human IgG1-Fc & His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 4 mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close