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Recombinant Human, Cynomolgus TWEAK/TNFSF12 Protein (mFc Tag)

Recombinant Human, Cynomolgus TWEAK/TNFSF12 Protein (mFc Tag)

Item no.	90094-C04H-2
Manufacturer	Sino Biological
Amount	2 mg
Quantity options	1 mg 2 mg 20 ug 4 mg 5 ug 50 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis
Type	Proteins
Specific against	Monkey (Cynomolgus, Simian)
Host	Human
Conjugate/Tag	Fc
Purity	(72.2+25.9) % as determined by SDS-PAGE
Sequence	Ser94-His249
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	90094-C04H
Similar products	TNFSF12
Available
Manufacturer - Type	Protein
Manufacturer - Conjugate / Tag	N-mouse IgG1-Fc
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	TNFSF12
Protein Construction	A DNA sequence encoding the cynomolgus TNFSF12 (F7HGN4) (Ser94-His249) was expressed with the Fc region of mouse IgG1 at the N-terminus. Cynomolgus and Human TNFSF12 sequences are identical.
Expressed Host	Human Cells
Bio-Activity	1. Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is typically 2-8 ng/mL. 2. Immobilized Cynomolgus mFc-TNFSF12 at 10 ug/ml (100 ul/well) can bind human Fc-TNFRSF12A (Cat:10431-H01H), The EC50 of human Fc-TNFRSF12A (Cat:10431-H01H) is 0.07-0.15 ug/ml.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Asp
Molecule Mass	The recombinant cynomolgus TNFSF12 is a disulfide-linked homodimer. The reduced monomer comprises 392 amino acids and has a calculated molecular mass of 43.8 KDa. The apparent molecular mass of it is approximately 34 and 47 KDa respectively in SDS-PAGE.
Formulation	Lyophilized from sterile PBS, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2 mg

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