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Human B7-H3 Protein, mFc-His Tag

Human B7-H3 Protein, mFc-His Tag

Item no.	DIM-PME100012-10ug
Manufacturer	DIMA Biotechnology
Amount	10 ug
Quantity options	100 ug 10 ug 50 ug
Category	Oncology By Cell Type Blastoma Carcinoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Mesothelioma
Type	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	HIS, Fc
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B7-H3,CD276,B7 homolog 3
Similar products	CD276, B7 homolog 3, B7-H3
Shipping Condition	Room temperature
Available
Manufacturer - Category	ECD Proteins
Manufacturer - Targets	B7-H3
Manufacturer - Conjugate / Tag	C-Mouse Fc and 6xHis Tag
Molecular Weight	The protein has a predicted molecular mass of 70-75 kDa after removal of the signal peptide.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Molecular Characterization	B7-H3(Leu29-Pro245) mFc(Pro99-Lys330) 6xHis
Description	Recombinant human B7-H3 protein with C-terminal mouse Fc and 6xHis tag
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 10/30/2025

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