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Human OX40 Protein, hFc-His tag

Human OX40 Protein, hFc-His tag

Item no.	DIM-PME100022-50ug
Manufacturer	DIMA Biotechnology
Amount	50 ug
Quantity options	100 ug 10 ug 50 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Western Blot
Type	Proteins
Format	Lyophilized
Applications	WB
Specific against	other
Host	HEK293
Conjugate/Tag	HIS, Fc
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TNFRSF4,OX40,CD134,OX40L receptor,ACT35,TXGP1L
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant
Manufacturer - Category	ECD Proteins
Manufacturer - Targets	OX40
Manufacturer - Conjugate / Tag	C-Human Fc and 6xHis Tag
Molecular Weight	The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide.
Buffer	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 29 % trehalose is added as protectants before lyophilization.
Purification	affinity purification
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4 T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Molecular Characterization	OX40(Leu29-Ala214) hFc(Glu99-Ala330) 6xHis tag
Description	Recombinant human OX40 protein with C-terminal human Fc and 6xHis tag
Reconstitution	Reconstitute with deionized water
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/30/2025

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