Human EPHA3 Protein, mFc-His Tag

C-Mouse Fc and 6xHis tag

The protein has a predicted molecular mass of 85.9 kDa after removal of the signal peptide.

Store at -80C for 12 months (Avoid repeated freezing and thawing)

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.