Comparison

Human IL5RA Protein, His Tag

Item no. DIM-PME100093-10ug
Manufacturer DIMA Biotechnology
Amount 10 ug
Quantity options 100 ug 10 ug 50 ug
Category
Type Proteins
Format Lyophilized
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag HIS
Purity The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL5Ra,CD125,IL-5 R alpha
Similar products CD125, IL5Ra, IL-5 R alpha
Shipping Condition Room temperature
Available
Manufacturer - Category
ECD Proteins
Manufacturer - Targets
IL5RA
Manufacturer - Conjugate / Tag
C-6xHis Tag
Molecular Weight
The protein has a predicted molecular mass of 37.0 kDa after removal of the signal peptide.The apparent molecular mass of IL5RA-His is approximately 50-55 kDa due to glycosylation.
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Molecular Characterization
IL5RA(Asp21-Pro338) 6xHis tag
Description
Recombinant human L5RA protein with C-terminal 6xHis tag
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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