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Human EGFR Protein, His Tag

Human EGFR Protein, His Tag

Item no.	DIM-PME100099-10ug
Manufacturer	DIMA Biotechnology
Amount	10 ug
Quantity options	100 ug 10 ug 50 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Western Blot Astrocytoma By Organ Bladder Cancer
Type	Proteins
Format	Lyophilized
Applications	WB
Specific against	other
Host	HEK293
Conjugate/Tag	HIS
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	EGFR, ERBB, ERBB1, HER1, PIG61, mENA
Shipping condition	Room temperature
Available
Manufacturer - Type	Recombinant
Manufacturer - Category	ECD Proteins
Manufacturer - Targets	EGFR
Manufacturer - Conjugate / Tag	C-6xHis Tag
Molecular Weight	The protein has a predicted molecular mass of 69.4 kDa after removal of the signal peptide.The apparent molecular mass of EGFR-His is approximately 100-130 kDa due to glycosylation.
Buffer	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 117 % trehalose is added as protectants before lyophilization.
Purification	affinity purification
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Molecular Characterization	EGFR(Leu25-Ser645) 6xHis tag
Description	Recombinant human EGFR Protein with C-terminal 6xHis tag
Reconstitution	Reconstitute with deionized water
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 7/31/2025

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