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Human PD-1 Protein, hFc-His tag

Human PD-1 Protein, hFc-His tag

Manufacturer	DIMA Biotechnology
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Peptides & Proteins Recombinant Proteins Myelofibrosis
Type	Proteins
Specific against	Human
Format	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 73 % trehalose is added as protectants before lyophilization.
Amount	10 ug
Host	HEK293
Item no.	DIM-PME100462-10ug
Targets	CD279
Conjugate/Tag	Fc, His
eClass 6.1	34160400
eClass 9.0	42020190
Available
Tags	C-Human Fc and 6xHis tag
Molecular Characterization	PD-1(Leu25-Gln167)+hFc(Glu99-Ala330)+6xHis tag
Molecular Weight	The protein has a predicted molecular mass of 42.9 kDa after removal of the signal peptide.
Purity	The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -80C for 12 months (Avoid repeated freezing and thawing)
Usage	Research use only
Background	This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

available

Delivery expected until 7/4/2024