Item no. |
DIM-PME100468-100ug |
Manufacturer |
DIMA Biotechnology
|
Amount |
100 ug |
Quantity options |
100 ug
10 ug
50 ug
|
Category |
|
Type |
Proteins |
Format |
Lyophilized |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 |
Conjugate/Tag |
HIS |
Purity |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CD217, CDw217, IL-17RA, IL17R, CANDF5, hIL-17R |
Similar products |
IL17R, CD217, CDw217, IL-17RA, hIL-17R, CANDF5 |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Category |
ECD Proteins |
Manufacturer - Targets |
IL17RA |
Manufacturer - Conjugate / Tag |
C-6xHis Tag |
Molecular Weight |
The protein has a predicted molecular mass of 34.3 kDa after removal of the signal peptide. |
Storage |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background |
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Molecular Characterization |
IL17RA(Leu33-Trp320) 6xHis tag |
Description |
Recombinant human IL17RA protein with C-terminal 6xHis tag |
Formulation & Reconstitution |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Usage |
Research use only |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.