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Human NRG1 Protein, hFc Tag

Human NRG1 Protein, hFc Tag

Item no.	DIM-PME101093-100ug
Manufacturer	DIMA Biotechnology
Amount	100 ug
Quantity options	100 ug 10 ug 50 ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling By Cell Type Carcinoma Melanoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Neuronal Cell Markers
Type	Proteins Recombinant
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Fc
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ARIA,GGF,GGF2,HGL,HRG,HRG1,HRGA,MST131,MSTP131,NDF,NRG1-IT2,SMDF
Shipping Condition	Room temperature
Available
Manufacturer - Category	ECD Proteins
Manufacturer - Targets	NRG1
Manufacturer - Conjugate / Tag	C-Human Fc Tag
Molecular Weight	The protein has a predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of NRG1-hFc is approximately 55-70 kDa due to glycosylation.
Buffer	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Purification	affinity purification
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
Molecular Characterization	NRG1 (Ser20-Arg242) hFc(Glu99-Ala330)
Description	Recombinant human NRG1 Protein with C-terminal Human Fc tag
Reconstitution	Reconstitute with deionized water
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/30/2025

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