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Human Ephrin-A1 / EFNA1 Protein, Fc Tag

Human Ephrin-A1 / EFNA1 Protein, Fc Tag

Item no.	EF1-H5251-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	95%
Citations	(1) Liu D.-P., et al., 2007, Int. J. Oncol. 30:865-871. (2) Wykosky J., et al., 2008, Oncogene 27:7260-7273.
NCBI	NP_004419.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	EFNA1,Ephrin-A1,LERK-1,TNFAIP4,EPLG1,B61,ECKLG,EFL1
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	46.0 kDa
Manufacturer - Format	Powder
Description	Ephrin-A1 (EFNA1) is also known as EPLG1, LERK1, TNFAIP4, Immediate early response protein B61, which belongs to the ephrin family. EFNA1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA1 is cell surface GPI-bound ligand for Eph receptors, and is a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA1 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA1 plays an important role in angiogenesis and tumor neovascularization.
Background	Ephrin-A1 (EFNA1) is also known as EPLG1, LERK1, TNFAIP4, Immediate early response protein B61, which belongs to the ephrin family. EFNA1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA1 is cell surface GPI-bound ligand for Eph receptors, and is a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA1 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA1 plays an important role in angiogenesis and tumor neovascularization.
Molecule	Ephrin-A1
Exp Region	Asp 19 - Ser 182
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 53-57 kDa under reducing (R) condition, and 100-115 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

EF1-H5251-1mg-datasheet.pdf

EF1-H5251-1mg-safety-datasheet.pdf