Product Description |
RuvA Protein, a central RuvA-RuvB-RuvC complex component, plays a key role in genetic recombination and DNA repair, particularly in processing Holliday junction (HJ) DNA. Collaborating with RuvB, RuvA facilitates HJ branch migration, binding to HJ cruciform DNA and conferring an open structure. The RuvB hexamer acts as a molecular pump in dissociating the junction. RuvA's specificity in binding to cruciform junctions and inhibiting RuvC endoDNase activity highlights its multifaceted functions in DNA repair and recombination. RuvA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived RuvA protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of RuvA Protein, E.coli (His-SUMO) is 203 a.a., with molecular weight of ~38.1 kDa. |