Product Description |
Profilin-2 Protein, a key player in protein folding, specifically binds to cytosolic chaperonin (c-CPN), facilitating the transfer of target proteins. It also interacts with nascent polypeptide chains, aiding proper folding amid various competing pathways for nonnative proteins. Comprising two PFD-alpha type and four PFD-beta type subunits, the heterohexameric structure of Profilin-2 is integral to the PAQosome complex. Collaborating with various members, including RUVBL1, RUVBL2, RPAP3, PIH1D1, PFDN6, PDRG1, UXT, URI1, ASDURF, POLR2E, and DNAAF10/WDR92, Profilin-2 contributes to the biogenesis of diverse protein complexes. Notably, the phosphorylation-dependent interaction with URI1 exhibits a growth-dependent pattern, highlighting intricate regulatory mechanisms in cellular processes. Profilin-2 Protein, Human (His) is the recombinant human-derived Profilin-2 protein, expressed by E. coli, with N-6*His labeled tag. The total length of Profilin-2 Protein, Human (His) is 140 a.a., with molecular weight of ~16 kDa. |