« Back
Home /
Rat LAG3 / CD223 Protein, His Tag (HPLC verified)

Rat LAG3 / CD223 Protein, His Tag (HPLC verified)

Item no.	LA3-R52H5-1mg
Manufacturer	ACROBiosystems
Amount	100 ug x 10
Quantity options	100 ug 100 ug x 10
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Rat (Rattus norvegicus)
Host	HEK293
Conjugate/Tag	Unconjugated, HIS
Purity	90%
Citations	(1) Triebel F., et al., 1990, J. Exp. Med. 171:1393-1405. (2) Baixeras E., et al., 1992, J. Exp. Med. 176:327-337.
NCBI	NP_997678
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LAG3,CD223,FDC
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag	C-10xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	47.6 kDa
Manufacturer - Format	Powder
Description	Rat LAG3, His Tag (LA3-R52H5) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Leu 442 (Accession # NP_997678).
Background	Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Molecule	LAG-3
Exp Region	Gly 24 - Leu 442
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.6 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH 7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

LA3-R52H5-1mg-datasheet.pdf

LA3-R52H5-1mg-safety-datasheet.pdf