Comparison

Recombinant human Protein C Inhibitor/SERPINA5 protein

Item no. NKM-ATGP3746-50ug
Manufacturer NKMAX
Amount 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug 5 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MHRHHPREMK KRVEDLHVGA TVAPSSRRDF TFDLYRALAS AAPSQNIFFS PVSISMSLAM LSLGAGSSTK MQILEGLGLN LQKSSEKELH RGFQQLLQEL NQPRDGFQLS LGNALFTDLV VDLQDTFVSA MKTLYLADTF PTNFRDSAGA MKQINDYVAK QTKGKIVDLL KNLDSNAVVI MVNYIFFKAK WETSFNHKGT QEQDFYVTSE TV
Citations Han MH., et al. (2008) Nature. 451(7182):1076-81.
Li W., et al. (2008) J Biol Chem. 283(51):36039-45.
NCBI AAH08915
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Serpin peptidase inhibitor,clade A,member 5,PAI3,PCI,PROCI,Plasma serine protease inhibitor,Acrosomal serine protease inhibitor,Plasminogen activator inhibitor 3,Protein C inhibitor,SERPINA5,PLANH3,Serine proteinase inhibitor clade A (alpha-1 antiproteinase,antitrypsin) member 5,Cysteine proteinase inhibitor clade A (alpha-1 antiproteinase,antitrypsin) member 5
Similar products PCI, PROCI, Serpin A5, PAI3, member 5, clade A, Serpin peptidase inhibitor, ATGP3746-10ug, ATGP3746-20ug, ATGP3746-50ug, ATGP3746-100ug, ATGP3746-250ug, ATGP3746-500ug, ATGP3746-1mg, ATGP3746-10, ATGP3746-20, ATGP3746-50, ATGP3746-100, ATGP3746-250, ATGP3746-500, ATGP3746-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
45.9 kDa (408aa) confirmed by MALDI-TOF
Description
Serpin A5, also known as PCI (Protein C Inhibitor) or PAI3 (plasminogen activator inhibitor 3), is a member of the serpin serine proteinase inhibitor family. This protein inhibits plasminogen activators as well as activated protein C. Serpin A5 is secreted in plasma, but is also expressed in liver. Serpin A5 is involved in cell inflammation, proliferation, apoptosis, tumor cell migration, invasion, and metastasis. Recombinant Serpin A5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM MES buffer (pH 6.0) containing 150mM NaCl, 10% glycerol
Antigen Species
Human
Gene Category
Cardiovascular
Domain
20-406aa
Bioactivity Comment Only
Measured by its ability to inhibit Thrombin cleavage of substrate Boc-VPR-AMC. The IC50 for this effect is less or equal to 2 nM
Species of Protein
Human
Manufacturer - Search Terms
Serpin A5, Serpin peptidase inhibitor, clade A, member 5, PAI3, PCI, PROCI, ATGP3746-10ug, ATGP3746-20ug, ATGP3746-50ug, ATGP3746-100ug, ATGP3746-250ug, ATGP3746-500ug, ATGP3746-1mg, ATGP3746-10, ATGP3746-20, ATGP3746-50, ATGP3746-100, ATGP3746-250, ATGP3746-500, ATGP3746-1
Manufacturer - Alternative Names
Serpin peptidase inhibitor, clade A, member 5, PAI3, PCI, PROCI, Plasma serine protease inhibitor, Acrosomal serine protease inhibitor, Plasminogen activator inhibitor 3, Protein C inhibitor, SERPINA5, PLANH3, Serine proteinase inhibitor clade A (alpha-1 antiproteinase, antitrypsin) member 5, Cysteine proteinase inhibitor clade A (alpha-1 antiproteinase, antitrypsin) member 5

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
available

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