Comparison

Recombinant Human Prolactin receptor/PRL-R Protein European Partner

Item no. RP00128-200ug
Manufacturer Abclonal
Amount 200 ug
Quantity options 100 ug 10 ug 200 ug 20 ug 50 ug 5 ug
Category
Type Proteins Recombinant
Specific against Human (Homo sapiens)
Host Human
Purity > 97% by SDS-PAGE.
NCBI Prolactin receptor/PRL-R
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias HPRL,MFAB,hPRLrI,PRLR,MFAB,hPRLrI
Shipping Condition Cool pack
Available
Manufacturer - Applications
< 0.1 EU/μg of the protein by LAL method.
Manufacturer - Category
Proteins
Shipping Temperature
ice pack
Storage Conditions
Store at -20°C.Store the lyophilized protein at -20°C to -80°C up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Protein Weight
25.26 kDa
Description
Recombinant Human Prolactin receptor/PRL-R Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln25-Asp234) of human PRLR/Prolactin Receptor (Accession #NP_000940.1) fused with a 6×His tag at the C-terminus.
Background
The protenin is a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Manufacturer - Cross Reactivity
Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Immunogen
Gln25-Asp234
Route
C-His
Manufacturer - Research Area
Growth Factor, Biosimilar Drug Targets
Revised name
HPRL, hPRLrI, MFAB
Antigen Seq
QLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMND
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized Human PRLR/Prolactin Receptor at 1 μg/mL (100 μL/well) can bind Prolactin Receptor Rabbit mAb with a linear range of 0. 67-3. 45 ng/mL.
Protein Formulation
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Expected Protein Size
25.26 kDa
Gene Symbol
Prolactin receptor/PRL-R

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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