Recombinant Human Frizzled-7/FZD7 Protein

< 0.1 EU/μg of the protein by LAL method.

ice pack

43.49 kDa

Frizzled-7 is a member of the Frizzled family of unconventional G-protein-coupled glycoprotein receptors for the Wnt signaling pathway. During development, Frizzled-7 is expressed during gastrulation and in the fetal gut, kidney and lung where it is thought to influence tissue morphogenesis via non-canonical signaling pathways . In the adult, Frizzled-7 is expressed in skeletal muscle, especially in satellite cells that mediate muscle regeneration in response to Wnt-7a. It is expressed in embryonic stem cells (ES), contributing to self-renewal signaling . Frizzled-7 expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

C-hFc&His

Fz-7, hFz7, FzE3

1. Measured by its binding ability in a functional ELISA. Immobilized Human Glypican-3 Protein at 5 μg/mL (100 μL/well) can bind Human FZD7 with a linear range of 4. 88-935. 5 ng/mL.|2. Measured by its binding ability in a functional ELISA. Immobilized Human Glypican-3 Protein at 5 μg/mL (100 μL/well) can bind Human FZD7 with a linear range of 4. 88-520. 4 ng/mL.

43.49 kDa