Recombinant Human IL-4 Protein

< 0.1 EU/μg of the protein by LAL method.

ice pack

15.8 kDa

Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It enhances both secretion and cell surface expression of IgE and IgG1. Interleukin-4 / IL4 also regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Interleukin-4 is essential for the switching of B cells to IgE antibody production and the maturation of T helper (Th) cells toward the Th2 phenotype.

C-His

BCGF-1, BCGF1, BSF-1, BSF1, IL-4, Interleukin-4

Measured in a cell proliferation assay using TF 1 human erythroleukemic cells. The ED₅₀ for this effect is 85-340 pg/mL, corresponding to a specific activity of 2. 94 × 10⁶~1. 17× 10⁷ units/mg.

15.8 kDa