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Mouse anti-IL-8/CXCL8 [+Biotin]

Mouse anti-IL-8/CXCL8 [+Biotin]

Manufacturer	Raybiotech
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Carcinoma ELISA Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	Human
Isotype	IgG1
Format	Supplied as lyophilized purified antibody. It can be reconstituted with sterile PBS before use. Please avoid freeze-thaw cycles.
Applications	ELISA
Amount	50 ug
Host	Mouse
Item no.	RB-IP-01-111B-50
Targets	CXCL8
eClass 6.1	32160702
eClass 9.0	32160702
Available
Target Name	IL-8/CXCL8
Accession Number	NM_000584
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= For Sandwich-based ELISA and membrane based assay, detecting level is up to 1pg/ml when it is used for capture), Western Blotting (recommended work dilution= 0.1-0.2 ug/ml)
Product Description	Interleukin-8, or IL-8, the prototypic member of the C-X-C, or alpha, family of chemokines, is a chemoattractant cytokine involved in the chemotaxis and activation of neutrophils. IL-8 expression has been correlated to a large number of chronic inflammatory diseases, including inflammatory bowel disease (IBD) and atherosclerosis. IL-8 is cleaved from a 99 amino acid precursor to a 72 amino acid, nonglycosylated, and biologically active protein. Whether IL-8 functions in vivo as a monomer or a hydrogen-bonded dimer has not yet been resolved. Two IL-8 receptors, designated IL-8RA and IL-8RB, have been described and share 77% sequence identity. Both are seven-transmembrane domain proteins (7TMD), similar to the G protein-coupled receptors, and, in addition to IL-8, serve as receptors for other members of the alpha and beta chemokine families.
Immunogen	Immunogen was recombinant protein derived from human IL-8. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.