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Recombinant Human IGFBP-7

Recombinant Human IGFBP-7

Manufacturer	Raybiotech
Category	Oncology Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Senescence By Organ Breast Cancer Testicular & Prostate Cancer
Type	Proteins
Specific against	Human
Amount	25 ug
Item no.	229-20186
Targets	IGFBP7
eClass 6.1	34160400
eClass 9.0	42020190
Available
Short Description	Purified recombinant IGFBP-7 expressed in E.coli.
Introduction	IGFBP-7 (insulin-like growth factor binding protein-7) is a secreted protein which belongs to a family of IGF-BPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II. IGFBP-7 is expressed in many tumour types and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation.
Protein Name	IGFBP-7
Molecular Weight (kDa)	26.4kD (257 amino acid residues).
Purity	>98% by SDS PAGE and HPLC analysis.
Formulation	10mM Sodium Phosphate, pH6.8
Concentration	ca.0.1 mg/ml after reconstitution
Preservative	None present
Endotoxin Level	<1EU/ug
Protein Type	Recombinant Protein
Recommended Applications	ELISA (0.2-0.4ng/well), Western Blotting (1.5-3.0ng/lane)
Reconstitution	Reconstitute with 0.25 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution. For extended storage the additiona of 0.1% BSA is recommended.
Storage/stability	Prior to reconstitution store at +4° C. After reconstitution store at -20° C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.