Comparison

Recombinant Human VISFATIN

Item no. 229-20192
Manufacturer Raybiotech
Amount 25 ug
Category
Type Proteins
Format Lyophilized
Applications FA
Specific against Human (Homo sapiens)
Host Hamster - Armenian
Purity >98% by SDS PAGE and HPLC analysis.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping Condition Room temperature
Available
Manufacturer - Category
Proteins|Recombinant Proteins|Human Proteins
Shipping Temperature
Ambient temperature
Storage Conditions
-20°C
Molecular Weight
52.5kD (465 amino acid residues).
Description
Purified recombinant visfatin expressed in E.coli.
UNSPSC Code
12352202
Formulation
10mM HCl
Protein Name & Synonyms
VISFATIN,
Format
Purified recombinant protein - lyophilized
Concentration
Total protein concentration ~0.1mg/ml after reconstitution.
Reconstitution
Reconstitute with 0.25ml distilled water.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution.

N.B. Due to solubility reasons, it is recommended that the solution be kept at low pH..
Endotoxin Level
<1EU/ug
Preservative
None present
Biological activity
The ED ₅₀ was determined by the dose-dependant proliferation of the RPMI 8226 cells. The expected ED ₅₀ for this effect is 15.0-20.0 ng/ml.
Introduction
Visfatin is a putative cytokine originally identified as PBEF (Pre-B cell-enhancing factor), subsequently determined to be a nicotinamide phosphoribosyltransferase (NAMPT) enzyme and member of the NAPRTase family, involved in catalyzing the biosynthesis of NAD from nicotinamide.

Visfatin is highly expressed in bone marrow, muscle and liver tissue and increases in expression in response to endotoxin, in amniotic epithelial cells following lipopolysaccharide (LPS) stimulation, and during the activation of T and B cells, dendritic cells and macrophages, suggesting a role in inflammatory processes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 ug
Available: In stock
available

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