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Mal-GGFG-PAB-MMAE

Mal-GGFG-PAB-MMAE

Item no.	HY-170512-25mg
Manufacturer	MedChem Express
CASRN	3055607-18-3
Amount	25 mg
Quantity options	1 ea 10 mg 25 mg 5 mg
Category	Reagents & Chemicals Ligands & Crosslinkers Crosslinkers
Type	Crosslinkers
Specific against	other
Purity	99.96
Citations	[1]Huang J, et al., Highly stable targeted linker-drug conjugate. US20240293570.
Smiles	O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC(CNC([C@@H](NC(CNC(CNC(CCN4C(C=CC4=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)OC)=O
ECLASS 10.1	32170205
ECLASS 11.0	32170205
UNSPSC	41105316
Shipping Condition	Cool pack
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Drug-Linker Conjugates for ADC
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	1336.57
Product Description	Mal-GGFG-PAB-MMAE (Compound 8) is a drug-linker conjugate, which is composed of the mitotic inhibitor MMAE (HY-15162) and the linker Mal-GGFG-PAB. Mal-GGFG-PAB-MMAE can be used for synthesis of antibody-drug conjugate[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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