Comparison

NVP-BHG712 European Partner

Item no. TMO-T6348-200mg
Manufacturer TargetMol
CASRN 940310-85-0
Amount 200 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 300 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Smiles Cc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Targets
Raf|||Src|||Ephrin Receptor|||Bcr-Abl
Storage Conditions
-20
Molecular Weight
503.48
Description
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Pathways
Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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