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NVP-BHG712

NVP-BHG712

Item no.	TMO-T6348-50mg
Manufacturer	TargetMol
CASRN	940310-85-0
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 300 mg 50 mg 5 mg
Category	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Reagents & Chemicals Molecules By Organ Heart & Blood Cancer
Type	Molecules
Specific against	other
Purity	0,98
Smiles	Cc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NVP-BHG712,NVP BHG712;NVPBHG712,Ephrin receptor inhibitor
Similar products	940310-85-0
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Raf\|\|\|Src\|\|\|Ephrin Receptor\|\|\|Bcr-Abl
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	503.48
Description	NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Pathways	Angiogenesis\|\|\|Cytoskeletal Signaling\|\|\|Tyrosine Kinase/Adaptors\|\|\|MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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