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AZD8330 (ARRY704; ARRY424704)

AZD8330 (ARRY704; ARRY424704)

Item no.	V0458-10mg
Manufacturer	InvivoChem LLC
CASRN	869357-68-6
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0458CAS #:869357-68-6Purity >=98% Description: AZD8330 (AZD-8330; ARRY-704; ARRY-424704) is an orally bioactive and non-ATP competitive (Allosteric) MEK 1/2 inhibitor with potential anticancer activity. It inhibits MEK1/2 with an IC50 of 7 nM. Description: References: Clin Cancer Res. 2007 Mar 1; 13(5):1576-83; Eur J Cancer. 2013 May; 49(7):1521-9.; Genes Cancer. 2015 Nov; 6(11-12):503-12. References:
Molecular Weight (MW)	461.23
Formula	C16H17FIN3O4
CAS No.	869357-68-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 92 mg/mL (199.5 mM)
	Water: < 1 mg/mL
	Ethanol: 92 mg/mL (199.5 mM)
Solubility (In vivo)	0.5% hydroxyethyl cellulose+0.1% Tween 80: 30mg/mL
Synonyms	ARRY704; AZD 8330; AZD8330; ARRY 424704; ARRY-424704; AZD-8330; ARRY424704; ARRY-704; ARRY 704. Chemical Name: 2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1, 5-dimethyl-6-oxo-1, 6-dihydropyridine-3-carboxamide. InChi Key: RWEVIPRMPFNTLO-UHFFFAOYSA-N InChi Code: InChI=1S/C16H17FIN3O4/c1-9-7-11(15(23)20-25-6-5-22)14(21(2)16(9)24)19-13-4-3-10(18)8-12(13)17/h3-4, 7-8, 19, 22H, 5-6H2, 1-2H3, (H, 20, 23) SMILES Code: O=C(C(C=C1C)=C(NC2=CC=C(I)C=C2F)N(C)C1=O)NOCCO

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Amount: 10 mg

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Delivery expected until 10/2/2025

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