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Telatinib (BAY 57-9352)

Telatinib (BAY 57-9352)

Item no.	V0532-25mg
Manufacturer	InvivoChem LLC
CASRN	332012-40-5
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0532CAS #:332012-40-5Purity >=98% Description: Telatinib (formerly BAY57-9352) is an orally bioavailable multi-kinase (e.g. VEGFR, PDGFR) inhibitor with potential antineoplastic activity. It inhibits VEGFR2/3, c-Kit and PDGFRalpha with IC50 values of 6 nM/4 nM, 1 nM and 15 nM, respectively. Telatinib was developed by Bayer company to reverse chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo. Description: References: Clin Cancer Res. 2008 Jun 1; 14(11):3470-6; Br J Cancer. 2008 Nov 18; 99(10):1579-85. References:
Molecular Weight (MW)	409.83
Formula	C20H16ClN5O3
CAS No.	332012-40-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 82 mg/mL (200.1 mM)
	Water: < 1 mg/mL
	Ethanol: 1 mg/mL (2.4 mM)
Other info	IUPAC/Chemical Name: 4-(((4-((4-chlorophenyl)amino)furo[2, 3-d]pyridazin-7-yl)oxy)methyl)-N-methylpicolinamide InChi Key: QFCXANHHBCGMAS-UHFFFAOYSA-N InChi Code: InChI=1S/C20H16ClN5O3/c1-22-19(27)16-10-12(6-8-23-16)11-29-20-17-15(7-9-28-17)18(25-26-20)24-14-4-2-13(21)3-5-14/h2-10H, 11H2, 1H3, (H, 22, 27)(H, 24, 25) SMILES Code: O=C(C1=NC=CC(COC2=NN=C(NC3=CC=C(Cl)C=C3)C4=C2OC=C4)=C1)NC
Synonyms	BAY-57-9352; BAY 57-9352; BAY 57-9352; BAY57-9352

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 25 mg

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Delivery expected until 10/2/2025

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