« Back
Home /
Alectinib (AF-802, CH-5424802, RO-5424802, Alecensa)

Alectinib (AF-802, CH-5424802, RO-5424802, Alecensa)

Item no.	V0606-100mg
Manufacturer	InvivoChem LLC
CASRN	1256580-46-7
Amount	100 mg
Quantity options	1 g 250 mg 2 g 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0606CAS #:1256580-46-7 (free base)Purity >=98% Description: Alectinib (formerly AF802, CH5424802, RO5424802; trade name Alecensa) is a potent, selective, and orally bioavailable ALK (anaplastic lymphoma kinase) tyrosine kinase inhibitor with potential antitumor activity. It inhibits ALK with IC50 value of 1.9 nM in cell-free assays. In 2017, Alectinib was approved by the Food and Drug Administration (FDA) for the treatment of patients with ALK-positive non-small cell lung cancer (NSCLC). Description: References: Cancer Cell. 2011 May 17; 19(5):679-90; Bioorg Med Chem. 2012 Feb 1; 20(3):1271-80. References: Related CAS: 1256589-74-8 (HCl); 1256580-46-7 (free base)
Molecular Weight (MW)	482.62
Formula	C30H34N4O2
CAS No.	1256580-46-7 (free base)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 0.5 mg/mL (1.0 mM)
	Water: < 1 mg/mL
	Ethanol:< 1 mg/mL
Solubility (In vivo)	30% PEG400+0.5% Tween80+5% propylene glycol: 30 mg/mL
Synonyms	Alectinib, CH5424802, CH 5424802, RO 5424802; AF802, CH-5424802, RO5424802, AF 802, AF-802, RO-5424802, brand name: Alecensa

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Delivery expected until 10/2/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer