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Alectinib (AF-802, CH-5424802, RO-5424802, Alecensa)

Alectinib (AF-802, CH-5424802, RO-5424802, Alecensa)

Item no.	V0606-250mg
Manufacturer	InvivoChem LLC
CASRN	1256580-46-7
Amount	250 mg
Quantity options	100 mg 1 g 2 g 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0606CAS #:1256580-46-7 (free base)Purity >=98% Description: Alectinib (formerly AF802, CH5424802, RO5424802; trade name Alecensa) is a potent, selective, and orally bioavailable ALK (anaplastic lymphoma kinase) tyrosine kinase inhibitor with potential antitumor activity. It inhibits ALK with IC50 value of 1.9 nM in cell-free assays. In 2017, Alectinib was approved by the Food and Drug Administration (FDA) for the treatment of patients with ALK-positive non-small cell lung cancer (NSCLC). Description: References: Cancer Cell. 2011 May 17; 19(5):679-90; Bioorg Med Chem. 2012 Feb 1; 20(3):1271-80. References: Related CAS: 1256589-74-8 (HCl); 1256580-46-7 (free base)
Molecular Weight (MW)	482.62
Formula	C30H34N4O2
CAS No.	1256580-46-7 (free base)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 0.5 mg/mL (1.0 mM)
	Water: < 1 mg/mL
	Ethanol:< 1 mg/mL
Solubility (In vivo)	30% PEG400+0.5% Tween80+5% propylene glycol: 30 mg/mL
Synonyms	Alectinib, CH5424802, CH 5424802, RO 5424802; AF802, CH-5424802, RO5424802, AF 802, AF-802, RO-5424802, brand name: Alecensa

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 10/2/2025

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