« Back
Home /
Diosmetin

Diosmetin

Item no.	V0810-1g
Manufacturer	InvivoChem LLC
CASRN	520-34-3
Amount	1 g
Quantity options	100 mg 250 mg 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0810CAS #:520-34-3Purity >=98% Description: Diosmetin (also known as DIO; HSDB 8101; HSDB 8101; Luteolin 4'-methyl ether) is a naturally occuring flavonoid found in spearmint, oregano, and many other plants with various biological activity (e.g, antioxidant, anti-inflammation, anticancer). It inhibits human CYP1A enzyme activity with an IC50 of 40 uM in HepG2 cell. Diosmetin is also an agonist of the aryl hydrocarbon receptor (AHR). It potently inhibited the enzyme activity of cytochrome P450 1A1 (CYP1A1) in a dose-dependent manner with an IC50 value of approximately 30 nM, in microsomes from MCF-7 cells. Description: References: Pharmacol Res. 1992 Dec; 26(4):395-402; Cancer Res. 1998 Jul 1; 58(13):2754-60. References:
Molecular Weight (MW)	300.26
Formula	C16H12O6
CAS No.	520-34-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 60 mg/mL (199.8 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: 5, 7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one InChi Key: MBNGWHIJMBWFHU-UHFFFAOYSA-N InChi Code: InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7, 17-19H, 1H3 SMILES Code: O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=CC(O)=CC(O)=C13
Synonyms	Luteolin 4-methyl ether; HSDB-8101; Diosmetin; HSDB 8101; HSDB 8101; Luteolin 4'-methyl ether

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 g

available

Delivery expected until 9/4/2025

Compare

Add to wishlist

Get an offer

Request delivery time