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Altretamine (ENT-50852)

Altretamine (ENT-50852)

Item no.	V2028-250mg
Manufacturer	InvivoChem LLC
CASRN	645-05-6
Amount	250 mg
Quantity options	100 mg 1 g 2 g 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2028CAS #:645-05-6 Purity >=98% Description: Altretamine (also known as Hexamethylmelamine, NSC13875, ENT50852, WR-95704) is an alkylating anticancer drug which also acts as a chemosterilant for male houseflies and other insects. Altretamine was approved by the U.S. FDA in 1990. It is indicated for use as a single agent in the palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with cisplatin and/or alkylating agent-based combination. The precise mechanism by which altretamine exerts its anti-cancer effect is unknown but it is classified by MeSH as an alkylating antineoplastic agent. References: Clin Pharmacokinet. 1995 Jun; 28(6):439-48. Related CAS #: 2975-00-0 (HCl) 645-05-6 (free base)
Molecular Weight (MW)	210.28
Formula	C9H18N6
CAS No.	645-05-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 15 mg/mL (71.3 mM)
	Water: < 1 mg/mL
	Ethanol: 33 mg/mL (156.9 mM)
Solubility (In vivo)	Chemical Name: N2, N2, N4, N4, N6, N6-hexamethyl-1, 3, 5-triazine-2, 4, 6-triamine InChi Key: UUVWYPNAQBNQJQ-UHFFFAOYSA-N InChi Code: InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3 SMILES Code: CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1
Synonyms	NSC-13875; ENT-50852; RB-1515; WR-95704; NSC 13875; ENT 50852; RB 1515; WR 95704; NSC13875; ENT50852; RB1515; WR95704; Hexamethylmelamine, Hemel; Hexaloids; Hexalen; Hexastat; Hexinawas; HMM; HXM;

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Amount: 250 mg

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Delivery expected until 11/6/2025

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