Comparison

RELEBACTAM

Item no. V4368-100mg
Manufacturer InvivoChem LLC
CASRN 1174018-99-5
Amount 100 mg
Quantity options 10 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V4368CAS #:1174018-99-5 Purity >=98%

Description: Relebactam (also known as MK-7655) is a diazabicyclooctane that acts as a potent and selective beta-lactamase inhibitor. It has activity against a wide spectrum of beta-lactamases, including class A (extended-spectrum beta-lactamases ESBLs and KPC) and class C (AmpC) enzymes. Relebactam reduced imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L. MK-7655 potentiated imipenem against Enterobacteriaceae with KPC carbapenemases or combinations of beta-lactamase and impermeability, but not those with metallo-carbapenemases. It augmented the activity of imipenem against P. aeruginosa in general and OprD mutants in particular.

References: Antimicrob Agents Chemother. 2015 Aug; 59(8):5029-31.; Int J Antimicrob Agents. 2015 Nov; 46(5):483-93.

Related CAS #: 1174020-13-3 (hydrate) 1174018-99-5 (free acid) 1502858-91-4 (sodium)

RELEBACTAM

Name: Relebactam
CAS#: 1174018-99-5 (free acid); 1502858-91-4 (sodium); 1174020-13-3 (hydrate); 1174018-99-5;
Chemical Formula: C12H20N4O6S
Exact Mass: 348.1104
Molecular Weight: 348.37
Elemental Analysis: 41.37; H, 5.79; N, 16.08; O, 27.55; S, 9.20
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: MK-7655; Relebactam; MK 7655; MK7655
Chemical Name: (1R, 2S, 5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1, 6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate
SMILES Code: O=S(O)(ON1[C]2([H])CC[CH](C(NC3CCNCC3)=O)[N](C2)C1=O)=O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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