NU6027

Item no.	TMO-T6612-200mg
Manufacturer	TargetMol
CASRN	220036-08-8
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C11H17N5O2
Smiles	Nc1nc(N)c(N=O)c(OCC2CCCCC2)n1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ATM/ATR\|\|\|DNA-PK\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	251.29
Description	NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.
Pathways	PI3K/Akt/mTOR signaling\|\|\|DNA Damage/DNA Repair\|\|\|Cell Cycle/Checkpoint
Bioactivity	NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 Î¼M/1.3 Î¼M, 0.4 Î¼M and 2.2 Î¼M, enter cells more readily than the 6-aminopurine-based inhibitors.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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