NU6027

Item no.	TMO-T6612-100mg
Manufacturer	TargetMol
CASRN	220036-08-8
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Citations	1. Arris CE, et al. J Med Chem, 2000, 43(15), 2797-2804.
Smiles	Nc1nc(N)c(N=O)c(OCC2CCCCC2)n1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ATM/ATR\|\|\|DNA-PK\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	251.29
Description	NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.
Pathways	PI3K/Akt/mTOR signaling\|\|\|DNA Damage/DNA Repair\|\|\|Cell Cycle/Checkpoint

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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