CDK12 Antibody

Item no.	CSB-PA882147LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Proliferation Primary Antibodies By Organ Bladder Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	arginine/serine-rich antibody,Cdc2 related kinase arginine/serine rich antibody,CDC2 related protein kinase 7 antibody,Cdc2-related kinase antibody,CDC2-related protein kinase 7 antibody,Cdk12 antibody,CDK12_HUMAN antibody,Cell division cycle 2 related protein kinase 7 antibody,Cell division cycle 2-related protein kinase 7 antibody,Cell division protein kinase 12 antibody,CRK7 antibody,CRKR antibody,CrkRS antibody,Cyclin-dependent kinase 12 antibody,EC 2.7.11.22 antibody,hCDK12 antibody,kiaa0904 antibody,Pksc antibody
Similar products	CDK12, Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12), CRK7 CRKRS KIAA0904
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; Recommended dilution: WB:1:500-1:5000
Manufacturer - Targets	CDK12
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	arginine/serine-rich antibody, Cdc2 related kinase arginine/serine rich antibody, CDC2 related protein kinase 7 antibody, Cdc2-related kinase antibody, CDC2-related protein kinase 7 antibody, Cdk12 antibody, CDK12_HUMAN antibody, Cell division cycle 2 related protein kinase 7 antibody, Cell division cycle 2-related protein kinase 7 antibody, Cell division protein kinase 12 antibody, CRK7 antibody, CRKR antibody, CrkRS antibody, Cyclin-dependent kinase 12 antibody, EC 2.7.11.22 antibody, hCDK12 antibody, kiaa0904 antibody, Pksc antibody
Immunogen Species	Human
Immunogen	Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:5000
Background	Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Signal Transduction
Initial Research Areas	Signal Transduction
Antigen Species	Human
Antigen	Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 11/6/2025

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