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Recombinant Human HER3/ERBB3 Protein (ECD, His Tag), HPLC-verified

Recombinant Human HER3/ERBB3 Protein (ECD, His Tag), HPLC-verified

Item no.	10201-H08H-20
Manufacturer	Sino Biological
Amount	20 ug
Quantity options	1 mg 10 ug 2 mg 20 ug 4 mg 50 ug 500 ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Astrocytoma By Organ Bladder Cancer Neuronal Cell Markers
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Conjugate/Tag	HIS
Purity	> 95 % as determined by SDS-PAGE
Sequence	Met1-Thr643
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	c-erbB-3,c-erbB3,EEBB3,ErbB-3,erbB3-S,HER3,LCCS2,MDA-BF-1,p180-ErbB3,p45-sErbB3,p85-sErbB3
Similar products	ERBB3
Available
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	ERBB3
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed, with a C-terminal polyhistidine tag.
Expressed Host	Human Cells
Bio-Activity	1. Measured by its binding ability in a functional ELISA. 2. Immobilized human ErbB3 at 2 ug/mL (100 ul/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.43 ug/mL.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Ser 20
Molecule Mass	The recombinant human ErbB3 protein consists of 635 amino acids after the removal of signal peptide and has a calculated molecular mass of 70.2 kDa. As a result of glycosylation, the recombinant ErbB3 migrates as an approximately 100-110 kDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.5

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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10201-H08H-20-safety-datasheet.pdf