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IL6 / IL-6 Neutralizing Antibody

IL6 / IL-6 Neutralizing Antibody

Item no.	10395-R508-200
Manufacturer	Sino Biological
Amount	200 ug
Quantity options	200 ug 500 ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Primary Antibodies
Type	Antibody Monoclonal
Clone	R508
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	sino
Available
Manufacturer - Type	Antibody
Storage Conditions	This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Antigen molecule name	IL6
Immunogen	Recombinant Human IL6 / IL-6 protein (Catalog#10395-HNAE)
Purification	Protein A
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human IL6 / IL-6 (rHuman IL6 / IL-6; Catalog#10395-HNAE; NP_000591.1; Val30-Met212) and was produced using recombinant antibody technology.
Specificity	Human IL6 / IL-6
Buffer	0.2 um filtered solution in PBS
No cross-reactivity	No cross-reactivity with rat IL6 (80076-RNAE) and mouse IL6 (50136-MNAE) in ELISA assay
Block	This IL6 Neutralizing Antibody can block the binding of recombinant IL6 (10395-HNAE) to its recombinant receptor IL6 Ralpha (10398-H08H).
Neutralization	The neutralization activity of IL6 Neutralizing Antibody is measured by its ability to neutralize IL6 induced proliferation in the T1165 mouse plasmacytoma cell line. The antibody Neutralizing Titer (IC50) is typically 20.5-82 ng/mL in the presence of 10 ng/mL Recombinant Human IL6 (10395-HNAE).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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